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Transcription factor binding at immunoglobulin enhancers is linked to somatic hypermutation targeting
Secondary diversification of the immunoglobulin (Ig) repertoire occurs through somatic hypermutation (SHM), gene conversion (GCV), and class switch recombination (CSR)—three processes that are initiated by activation-induced cytidine deaminase (AID). AID targets Ig genes at rates orders of magnitude...
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| Vydáno v: | Eur J Immunol |
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| Hlavní autoři: | , , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7202714/ https://ncbi.nlm.nih.gov/pubmed/31821534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201948357 |
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