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SIRT1 regulates O-GlcNAcylation of tau through OGT
Tau is modified with O-GlcNAcylation extensively in human brain. The O-GlcNAcylation levels of tau are decreased in Alzheimer’s disease (AD) brain. Sirtuin type 1 (SIRT1) is an enzyme that deacetylates proteins including transcriptional factors and associates with neurodegenerative diseases, such as...
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| 出版年: | Aging (Albany NY) |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7202539/ https://ncbi.nlm.nih.gov/pubmed/32310828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103062 |
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