Bis-benzylidine Piperidone RA190 treatment of hepatocellular carcinoma via binding RPN13 and inhibiting NF-κB signaling

BACKGROUND: According to GLOBOSCAN, hepatocellular carcinoma (HCC) claimed 782,000 lives in 2018. The tyrosine kinase inhibitor sofafenib is used to treat HCC, but new anticancer agents targeting different pathways are urgently needed to improve outcomes for patients with advanced disease. The aberr...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:BMC Cancer
Asıl Yazarlar: Soong, Ruey-Shyang, Anchoori, Ravi K., Roden, Richard B. S., Cho, Rou-Ling, Chen, Yi-Chan, Tseng, Sheng-Chieh, Huang, Yun-Li, Liao, Po-Cheng, Shyu, Yu-Chiau
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7201939/
https://ncbi.nlm.nih.gov/pubmed/32375699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-06896-0
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