RPN13/ADRM1 inhibitor reverses immunosuppression by myeloid-derived suppressor cells

Myeloid-derived-suppressor cells (MDSCs) are key mediators of immune suppression in the ovarian tumor microenvironment. Modulation of MDSC function to relieve immunosuppression may enhance the immunologic clearance of tumors. The bis-benzylidine piperidone RA190 binds to the ubiquitin receptor RPN13...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Soong, Ruey-Shyang, Anchoori, Ravi K., Yang, Benjamin, Yang, Andrew, Tseng, Ssu-Hsueh, He, Liangmei, Tsai, Ya-Chea, Roden, Richard B.S., Hung, Chien-Fu
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340091/
https://ncbi.nlm.nih.gov/pubmed/27655678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12095
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