טוען...
GCN2 drives macrophage and MDSC function and immune suppression in the tumor microenvironment.
GCN2 is an environmental sensor controlling transcription and translation in response to nutrient availability. While GCN2 is a putative therapeutic target for immuno-oncology, its role in shaping the immune response to tumors is poorly understood. Here we used mass cytometry, transcriptomics, and t...
שמור ב:
| הוצא לאור ב: | Sci Immunol |
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| Main Authors: | , , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7201901/ https://ncbi.nlm.nih.gov/pubmed/31836669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aax8189 |
| תגים: |
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