When defense turns into attack: Antiviral cytidine deaminases linked to somatic mutagenesis in HPV-associated cancer

Por Henderson, Stephen, Chakravarthy, Ankur, Fenton, Tim
Publicado no Mol Cell Oncol (2014)

TGF-β-associated extracellular matrix genes link cancer-associated fibroblasts to immune evasion and immunotherapy failure

Por Chakravarthy, Ankur, Khan, Lubaba, Bensler, Nathan Peter, Bose, Pinaki, De Carvalho, Daniel D.
Publicado no Nat Commun (2018)

ChAMP: 450k Chip Analysis Methylation Pipeline

Por Morris, Tiffany J., Butcher, Lee M., Feber, Andrew, Teschendorff, Andrew E., Chakravarthy, Ankur R., Wojdacz, Tomasz K., Beck, Stephan
Publicado em 2014

Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx

Por Chakravarthy, Ankur, Henderson, Stephen, Thirdborough, Stephen M., Ottensmeier, Christian H., Su, Xiaoping, Lechner, Matt, Feber, Andrew, Thomas, Gareth J., Fenton, Tim R.
Publicado no J Clin Oncol (2016)

The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2

Por Hartwig, Torsten, Montinaro, Antonella, von Karstedt, Silvia, Sevko, Alexandra, Surinova, Silvia, Chakravarthy, Ankur, Taraborrelli, Lucia, Draber, Peter, Lafont, Elodie, Arce Vargas, Frederick, El-Bahrawy, Mona A., Quezada, Sergio A., Walczak, Henning
Publicado no Mol Cell (2017)

Pan-cancer deconvolution of tumour composition using DNA methylation

Por Chakravarthy, Ankur, Furness, Andrew, Joshi, Kroopa, Ghorani, Ehsan, Ford, Kirsty, Ward, Matthew J., King, Emma V., Lechner, Matt, Marafioti, Teresa, Quezada, Sergio A., Thomas, Gareth J., Feber, Andrew, Fenton, Tim R.
Publicado no Nat Commun (2018)

Author Correction: Pan-cancer deconvolution of tumour composition using DNA methylation

Por Chakravarthy, Ankur, Furness, Andrew, Joshi, Kroopa, Ghorani, Ehsan, Ford, Kirsty, Ward, Matthew J., King, Emma V., Lechner, Matt, Marafioti, Teresa, Quezada, Sergio A., Thomas, Gareth J., Feber, Andrew, Fenton, Tim R.
Publicado no Nat Commun (2018)

Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma

Por Lechner, Matthias, Fenton, Tim, West, James, Wilson, Gareth, Feber, Andrew, Henderson, Stephen, Thirlwell, Christina, Dibra, Harpreet K, Jay, Amrita, Butcher, Lee, Chakravarthy, Ankur R, Gratrix, Fiona, Patel, Nirali, Vaz, Francis, O'Flynn, Paul, Kalavrezos, Nicholas, Teschendorff, Andrew E, Boshoff, Chris, Beck, Stephan
Publicado em 2013

LSD1 ablation stimulates anti-tumor immunity and enables checkpoint blockade

Por Sheng, Wanqiang, LaFleur, Martin W., Nguyen, Thao H., Chen, Sujun, Chakravarthy, Ankur, Conway, Jake Ryan, Li, Ying, Chen, Hao, Yang, Henry, Hsu, Pang-Hung, Van Allen, Eliezer M., Freeman, Gordon J., De Carvalho, Daniel D., He, Housheng Hansen, Sharpe, Arlene H., Shi, Yang
Publicado no Cell (2018)

CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma

Por Feber, Andrew, Worth, Daniel C., Chakravarthy, Ankur, de Winter, Patricia, Shah, Kunal, Arya, Manit, Saqib, Muhammad, Nigam, Raj, Malone, Peter R., Tan, Wei Shen, Rodney, Simon, Freeman, Alex, Jameson, Charles, Wilson, Gareth A., Powles, Tom, Beck, Stephan, Fenton, Tim, Sharp, Tyson V., Muneer, Asif, Kelly, John D.
Publicado no Cancer Res (2016)

GCN2 drives macrophage and MDSC function and immune suppression in the tumor microenvironment.

Por Halaby, Marie Jo, Hezaveh, Kebria, Lamorte, Sara, Ciudad, M. Teresa, Kloetgen, Andreas, MacLeod, Bethany L., Guo, Mengdi, Chakravarthy, Ankur, Medina, Tiago Da Silva, Ugel, Stefano, Tsirigos, Aristotelis, Bronte, Vincenzo, Munn, David H., Pugh, Trevor J., DeCarvalho, Daniel D., Butler, Marcus O., Ohashi, Pamela S., Brooks, David G., McGaha, Tracy L.
Publicado no Sci Immunol (2019)

Apoptotic cell–induced, TLR9-dependent AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans

Por Shinde, Rahul, Hezaveh, Kebria, Halaby, Marie Jo, Kloetgen, Andreas, Chakravarthy, Ankur, da Silva Medina, Tiago, Deol, Reema, Manion, Kieran P., Baglaenko, Yuriy, Eldh, Maria, Lamorte, Sara, Wallace, Drew, Chodisetti, Sathi Babu, Ravishankar, Buvana, Liu, Haiyun, Chaudhary, Kapil, Munn, David H., Tsirigos, Aristotelis, Madaio, Michael, Gabrielsson, Susanne, Touma, Zahi, Wither, Joan, De Carvalho, Daniel D., McGaha, Tracy L.
Publicado no Nat Immunol (2018)

An open-label, phase II multicohort study of an oral hypomethylating agent CC-486 and durvalumab in advanced solid tumors

Por Taylor, Kirsty, Loo Yau, Helen, Chakravarthy, Ankur, Wang, Ben, Shen, Shu Yi, Ettayebi, Ilias, Ishak, Charles A, Bedard, Philippe L, Abdul Razak, Albiruni, R Hansen, Aaron, Spreafico, Anna, Cescon, Dave, Butler, Marcus O, Oza, Amit M, Lheureux, Stephanie, Stjepanovic, Neda, Van As, Brendan, Boross-Harmer, Sarah, Wang, Lisa, Pugh, Trevor J, Ohashi, Pamela S, Siu, Lillian L, De Carvalho, Daniel D
Publicado no J Immunother Cancer (2020)