Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx

PURPOSE: In squamous cell carcinomas of the head and neck (HNSCC), the increasing incidence of oropharyngeal squamous cell carcinomas (OPSCCs) is attributable to human papillomavirus (HPV) infection. Despite commonly presenting at late stage, HPV-driven OPSCCs are associated with improved prognosis...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Chakravarthy, Ankur, Henderson, Stephen, Thirdborough, Stephen M., Ottensmeier, Christian H., Su, Xiaoping, Lechner, Matt, Feber, Andrew, Thomas, Gareth J., Fenton, Tim R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2016
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ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477823/
https://ncbi.nlm.nih.gov/pubmed/27863190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.68.2955
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