Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx

PURPOSE: In squamous cell carcinomas of the head and neck (HNSCC), the increasing incidence of oropharyngeal squamous cell carcinomas (OPSCCs) is attributable to human papillomavirus (HPV) infection. Despite commonly presenting at late stage, HPV-driven OPSCCs are associated with improved prognosis...

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Veröffentlicht in:J Clin Oncol
Hauptverfasser: Chakravarthy, Ankur, Henderson, Stephen, Thirdborough, Stephen M., Ottensmeier, Christian H., Su, Xiaoping, Lechner, Matt, Feber, Andrew, Thomas, Gareth J., Fenton, Tim R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477823/
https://ncbi.nlm.nih.gov/pubmed/27863190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2016.68.2955
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