Interleukin 22 Signaling Regulates Acinar Cell Plasticity to Promote Pancreatic Tumor Development in Mice

BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy that invades surrounding structures and metastasizes rapidly. Although inflammation is associated with tumor formation and progression, little is known about the mechanisms of this connection. We investigate t...

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Détails bibliographiques
Publié dans:Gastroenterology
Auteurs principaux: Lanfranca, Mirna Perusina, Zhang, Yaqing, Girgis, Alexander, Kasselman, Samantha, Lazarus, Jenny, Kryczek, illlona, Delrosario, Lawrence, Rhim, Andrew, Koneva, Lada, Sartor, Maureen, Sun, Lei, Halbrook, Christopher, Nathan, Hari, Shj, Jiaqi, Crawford, Howard C., di Magliano, Marina Pasca, Zo, Weiping, Franke, Timothy L.
Format: Artigo
Langue:Inglês
Publié: 2019
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197347/
https://ncbi.nlm.nih.gov/pubmed/31843590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.12.010
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