Interleukin 22 Signaling Regulates Acinar Cell Plasticity to Promote Pancreatic Tumor Development in Mice

BACKGROUND & AIMS: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy that invades surrounding structures and metastasizes rapidly. Although inflammation is associated with tumor formation and progression, little is known about the mechanisms of this connection. We investigate t...

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Detalhes bibliográficos
Publicado no:Gastroenterology
Main Authors: Lanfranca, Mirna Perusina, Zhang, Yaqing, Girgis, Alexander, Kasselman, Samantha, Lazarus, Jenny, Kryczek, illlona, Delrosario, Lawrence, Rhim, Andrew, Koneva, Lada, Sartor, Maureen, Sun, Lei, Halbrook, Christopher, Nathan, Hari, Shj, Jiaqi, Crawford, Howard C., di Magliano, Marina Pasca, Zo, Weiping, Franke, Timothy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197347/
https://ncbi.nlm.nih.gov/pubmed/31843590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.12.010
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