Tracking macrophage infiltration in a mouse model of pancreas cancer with the PET tracer [11C]PBR28

BACKGROUND: The tumor microenvironment of pancreatic ductal adenocarcinoma (PDAC) contains abundant immunosuppressive tumor associated macrophages (TAM). High level of infiltration is associated with poor outcome and is thought to represent a major roadblock to lymphocyte based immunotherapy. Effort...

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Pubblicato in:J Surg Res
Autori principali: Lanfranca, Mirna Perusina, Lazarus, Jenny, Shao, Xia, Nathan, Hari, Magliano, Marina Pasca Di, Zou, Weiping, Piert, Morand, Frankel, Timothy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6251503/
https://ncbi.nlm.nih.gov/pubmed/30463776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2018.07.015
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