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Impact of 1,N(6)-ethenoadenosine, a damaged ribonucleotide in DNA, on translesion synthesis and repair
Incorporation of ribonucleotides into DNA can severely diminish genome integrity. However, how ribonucleotides instigate DNA damage is poorly understood. In DNA, they can promote replication stress and genomic instability and have been implicated in several diseases. We report here the impact of the...
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| Published in: | J Biol Chem |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Biochemistry and Molecular Biology
2020
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7196658/ https://ncbi.nlm.nih.gov/pubmed/32213600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.012829 |
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