Cargando...
Intrinsic GTPase Activity of K-RAS Monitored by Native Mass Spectrometry
Mutations in RAS are associated with many different cancers and have been a therapeutic target for more than three decades. RAS cycles from an active to inactive state by both intrinsic and GTPase-activating protein (GAP)-stimulated hydrolysis. The activated enzyme interacts with downstream effector...
Guardado en:
| Publicado en: | Biochemistry |
|---|---|
| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7196336/ https://ncbi.nlm.nih.gov/pubmed/31306575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.9b00532 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|