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Fourier Transform-Ion Mobility-Orbitrap Mass Spectrometer: A Next-Generation Instrument for Native Mass Spectrometry

A new instrument configuration for native ion mobility-mass spectrometry (IM-MS) is described. Macromolecule ions are generated by using a static ESI source coupled to an RF ion funnel, and these ions are then mobility and mass analyzed using a periodic focusing drift tube IM analyzer and an Orbitra...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Poltash, Michael L., McCabe, Jacob W., Shirzadeh, Mehdi, Laganowsky, Arthur, Clowers, Brian H., Russell, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6464636/
https://ncbi.nlm.nih.gov/pubmed/30091588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b02463
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