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New Insights into the Metal-Induced Oxidative Degradation Pathways of Transthyretin
The amyloidogenic mechanism of transthyretin is still debated but understanding it fully could lend insight into disease progression and potential therapeutics. Transthyretin was investigated revealing a metal-induced (Cr/Cu) oxidation pathway leading to N-terminal backbone fragmentation and oligome...
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| Publicado no: | Chem Commun (Camb) |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6452628/ https://ncbi.nlm.nih.gov/pubmed/30887985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c9cc00682f |
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