Impaired Myofibroblast Dedifferentiation Contributes to Nonresolving Fibrosis in Aging

Idiopathic pulmonary fibrosis (IPF) is a fatal age-associated disease with no cure. Although IPF is widely regarded as a disease of aging, the cellular mechanisms that contribute to this age-associated predilection remain elusive. In this study, we sought to evaluate the consequences of senescence o...

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Bibliografiske detaljer
Udgivet i:Am J Respir Cell Mol Biol
Main Authors: Kato, Kosuke, Logsdon, Naomi J., Shin, Yoon-Joo, Palumbo, Sunny, Knox, Adam, Irish, Joseph D., Rounseville, Skye P., Rummel, Sydney R., Mohamed, Mohamed, Ahmad, Kareem, Trinh, Johnny M., Kurundkar, Deepali, Knox, Kenneth S., Thannickal, Victor J., Hecker, Louise
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193787/
https://ncbi.nlm.nih.gov/pubmed/31962055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2019-0092OC
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