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Reversal of Persistent Fibrosis in Aging by Targeting Nox4-Nrf2 Redox Imbalance
The incidence and prevalence of pathological fibrosis increase with advancing age, although mechanisms for this association are unclear. We assessed the capacity for repair of lung injury in young (2 months) and aged (18 months) mice. While the severity of fibrosis was not significantly different be...
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| Publicado no: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4545252/ https://ncbi.nlm.nih.gov/pubmed/24718857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008182 |
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