Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis

Matrix stiffening and myofibroblast resistance to apoptosis are cardinal features of chronic fibrotic diseases involving diverse organ systems. The interactions between altered tissue biomechanics and cellular signaling that sustain progressive fibrosis are not well defined. In this study, we used e...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhou, Yong, Huang, Xiangwei, Hecker, Louise, Kurundkar, Deepali, Kurundkar, Ashish, Liu, Hui, Jin, Tong-Huan, Desai, Leena, Bernard, Karen, Thannickal, Victor J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3582144/
https://ncbi.nlm.nih.gov/pubmed/23434591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66700
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