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Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis
Matrix stiffening and myofibroblast resistance to apoptosis are cardinal features of chronic fibrotic diseases involving diverse organ systems. The interactions between altered tissue biomechanics and cellular signaling that sustain progressive fibrosis are not well defined. In this study, we used e...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3582144/ https://ncbi.nlm.nih.gov/pubmed/23434591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI66700 |
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