The influence of genetic polymorphisms in drug metabolism enzymes and transporters on the pharmacokinetics of different fluvastatin formulations

The purpose of the present study was to investigate the impact of genetic polymorphism on fluvastatin pharmacokinetics. In addition, we compared the fluvastatin pharmacokinetics differences between extended-release (ER) 80 mg tablet and immediate-release (IR) 40 mg capsule in terms of drug metabolis...

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Vydáno v:Asian J Pharm Sci
Hlavní autoři: Xiang, Qian, Wu, Weidang, Zhao, Nan, Li, Chuan, Xu, Junyu, Ma, Lingyue, Zhang, Xiaodan, Xie, Qiufen, Zhang, Zhuo, Wang, Jiancheng, Xu, Weiren, Zhao, Xia, Cui, Yimin
Médium: Artigo
Jazyk:Inglês
Vydáno: Shenyang Pharmaceutical University 2020
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Research article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193447/
https://ncbi.nlm.nih.gov/pubmed/32373204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2019.06.002
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