The influence of genetic polymorphisms in drug metabolism enzymes and transporters on the pharmacokinetics of different fluvastatin formulations

The purpose of the present study was to investigate the impact of genetic polymorphism on fluvastatin pharmacokinetics. In addition, we compared the fluvastatin pharmacokinetics differences between extended-release (ER) 80 mg tablet and immediate-release (IR) 40 mg capsule in terms of drug metabolis...

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Pubblicato in:Asian J Pharm Sci
Autori principali: Xiang, Qian, Wu, Weidang, Zhao, Nan, Li, Chuan, Xu, Junyu, Ma, Lingyue, Zhang, Xiaodan, Xie, Qiufen, Zhang, Zhuo, Wang, Jiancheng, Xu, Weiren, Zhao, Xia, Cui, Yimin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Shenyang Pharmaceutical University 2020
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Research article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193447/
https://ncbi.nlm.nih.gov/pubmed/32373204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2019.06.002
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