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The influence of genetic polymorphisms in drug metabolism enzymes and transporters on the pharmacokinetics of different fluvastatin formulations

The purpose of the present study was to investigate the impact of genetic polymorphism on fluvastatin pharmacokinetics. In addition, we compared the fluvastatin pharmacokinetics differences between extended-release (ER) 80 mg tablet and immediate-release (IR) 40 mg capsule in terms of drug metabolis...

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Detalhes bibliográficos
Main Authors: Qian Xiang, Weidang Wu, Nan Zhao, Chuan Li, Junyu Xu, Lingyue Ma, Xiaodan Zhang, Qiufen Xie, Zhuo Zhang, Jiancheng Wang, Weiren Xu, Xia Zhao, Yimin Cui
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-03-01
Colecção:Asian Journal of Pharmaceutical Sciences
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1818087619302922
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