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Formulation and pharmacokinetic evaluation of a paclitaxel nanosuspension for intravenous delivery
Paclitaxel is a diterpenoid isolated from Taxus brevifolia. It is effective for various cancers, especially ovarian and breast cancer. Due to its aqueous insolubility, it is administered dissolved in ethanol and Cremophor(®) EL (BASF, Ludwigshafen, Germany), which can cause serious allergic reaction...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Dove Medical Press
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3141875/ https://ncbi.nlm.nih.gov/pubmed/21796250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S21097 |
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