Pharmacokinetic evaluation of a 1,3-dicyclohexylurea nanosuspension formulation to support early efficacy assessment

Time and resource constraints necessitate increasingly early decisions to advance or halt pre-clinical drug discovery programs. Early discovery or “tool” compounds may be potent inhibitors of new targets, but all too often they exhibit poor pharmaceutical and pharmacokinetic properties that make ear...

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Bibliografiska uppgifter
Huvudupphovsmän: Wahlstrom, Jan L, Chiang, Po-Chang, Ghosh, Sarbani, Warren, Chad J, Wene, Steve P, Albin, Lesley A, Smith, Mark E, Roberds, Steven L
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer 2007
Ämnen:
Nano Express
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3246351/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11671-007-9063-7
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