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The influence of genetic polymorphisms in drug metabolism enzymes and transporters on the pharmacokinetics of different fluvastatin formulations

The purpose of the present study was to investigate the impact of genetic polymorphism on fluvastatin pharmacokinetics. In addition, we compared the fluvastatin pharmacokinetics differences between extended-release (ER) 80 mg tablet and immediate-release (IR) 40 mg capsule in terms of drug metabolis...

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Publicado en:Asian J Pharm Sci
Main Authors: Xiang, Qian, Wu, Weidang, Zhao, Nan, Li, Chuan, Xu, Junyu, Ma, Lingyue, Zhang, Xiaodan, Xie, Qiufen, Zhang, Zhuo, Wang, Jiancheng, Xu, Weiren, Zhao, Xia, Cui, Yimin
Formato: Artigo
Idioma:Inglês
Publicado: Shenyang Pharmaceutical University 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7193447/
https://ncbi.nlm.nih.gov/pubmed/32373204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajps.2019.06.002
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