Sestrin2 Mediates IL-4-induced IgE Class Switching by Enhancing Germline ε Transcription in B Cells

Sestrin2 (Sesn2), a metabolic regulator, accumulates in response to a diverse array of cellular stresses. Sesn2 regulates cellular metabolism by inhibiting the mammalian target of rapamycin complex 1 through the AMP-activated protein kinase (AMPK) signaling pathway. Recently, researchers reported th...

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Detalhes bibliográficos
Publicado no:Immune Netw
Main Authors: Shim, You-Sun, Lee, Solji, Park, Hwan-Woo, Park, Seok-Rae
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Association of Immunologists 2020
Assuntos:
Brief Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192835/
https://ncbi.nlm.nih.gov/pubmed/32395371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4110/in.2020.20.e19
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