Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection

The primary reservoir for HIV is within memory CD4+ T cells residing within tissues, yet the features that make some of these cells more susceptible than others to infection by HIV is not well understood. Recent studies demonstrated that CCR5-tropic HIV-1 efficiently enters tissue-derived memory CD4...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Hsiao, Feng, Frouard, Julie, Gramatica, Andrea, Xie, Guorui, Telwatte, Sushama, Lee, Guinevere Q., Roychoudhury, Pavitra, Schwarzer, Roland, Luo, Xiaoyu, Yukl, Steven A., Lee, Sulggi, Hoh, Rebecca, Deeks, Steven G., Jones, R. Brad, Cavrois, Marielle, Greene, Warner C., Roan, Nadia R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7192375/
https://ncbi.nlm.nih.gov/pubmed/32353080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008450
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