Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir

The latent reservoir is a major barrier to HIV cure. As latently infected cells cannot be phenotyped directly, the features of the in vivo reservoir have remained elusive. Here, we describe a method that leverages high-dimensional phenotyping using CyTOF to trace latently infected cells reactivated...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Neidleman, Jason, Luo, Xiaoyu, Frouard, Julie, Xie, Guorui, Hsiao, Feng, Ma, Tongcui, Morcilla, Vincent, Lee, Ashley, Telwatte, Sushama, Thomas, Reuben, Tamaki, Whitney, Wheeler, Benjamin, Hoh, Rebecca, Somsouk, Ma, Vohra, Poonam, Milush, Jeffrey, James, Katherine Sholtis, Archin, Nancie M, Hunt, Peter W, Deeks, Steven G, Yukl, Steven A, Palmer, Sarah, Greene, Warner C, Roan, Nadia R
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2020
Assuntos:
Microbiology and Infectious Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7524554/
https://ncbi.nlm.nih.gov/pubmed/32990219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.60933
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