Shared Mechanisms Govern HIV Transcriptional Suppression in Circulating CD103(+) and Gut CD4(+) T Cells

Latent HIV infection is the main barrier to cure, and most HIV-infected cells reside in the gut, where distinct but unknown mechanisms may promote viral latency. Transforming growth factor β (TGF-β), which induces the expression of CD103 on tissue-resident memory T cells, has been implicated in HIV...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Yukl, Steven A., Khan, Shahzada, Chen, Tsui-Hua, Trapecar, Martin, Wu, Frank, Xie, Guorui, Telwatte, Sushama, Fulop, Daniel, Pico, Alexander R., Laird, Gregory M., Ritter, Kristen D., Jones, Norman G., Lu, Chuanyi M., Siliciano, Robert F., Roan, Nadia R., Milush, Jeffrey M., Somsouk, Ma, Deeks, Steven G., Hunt, Peter W., Sanjabi, Shomyseh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7944458/
https://ncbi.nlm.nih.gov/pubmed/33115867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01331-20
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