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eIF2B and the Integrated Stress Response: a structural and mechanistic view
The eukaryotic translation initiation factor eIF2 is a GTPase, which brings the initiator Met-tRNA(i) to the ribosome as the eIF2-GTP•Met-tRNA(i) ternary complex (TC). TC regeneration is catalyzed by the guanine nucleotide exchange factor (GEF) eIF2B. eIF2 phosphorylation by several stress-induced k...
Gorde:
| Argitaratua izan da: | Biochemistry |
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| Egile Nagusiak: | , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7189779/ https://ncbi.nlm.nih.gov/pubmed/32200625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00132 |
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