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eIF2B Mechanisms of Action and Regulation: A Thermodynamic View
Eukaryotic translation initiation factor 2B (eIF2B) is the guanine nucleotide exchange factor of the GTPase eIF2, which brings the initiator Met-tRNA(i) to the ribosome in the form of the eIF2-GTP·Met-tRNA(i) ternary complex (TC). The activity of eIF2B is inhibited by phosphorylation of its substrat...
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| Pubblicato in: | Biochemistry |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5840040/ https://ncbi.nlm.nih.gov/pubmed/29425030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00957 |
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