Insights into the Architecture of the eIF2Bα/β/δ Regulatory Subcomplex

[Image: see text] Eukaryotic translation initiation factor 2B (eIF2B), the guanine nucleotide exchange factor for the G-protein eIF2, is one of the main targets for the regulation of protein synthesis. The eIF2B activity is inhibited in response to a wide range of stress factors and diseases, includ...

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Main Authors: Bogorad, Andrew M., Xia, Bing, Sandor, Dana G., Mamonov, Artem B., Cafarella, Tanya R., Jehle, Stefan, Vajda, Sandor, Kozakov, Dima, Marintchev, Assen
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4045321/
https://ncbi.nlm.nih.gov/pubmed/24811713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi500346u
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