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TLR4-mediated pyroptosis in human hepatoma-derived HuH-7 cells induced by a branched-chain polyunsaturated fatty acid, geranylgeranoic acid
A branched-chain polyunsaturated fatty acid, geranylgeranoic acid (GGA; C(20:4)), which is an endogenous metabolite derived from the mevalonate pathway in mammals, has been reported to induce cell death in human hepatoma cells. We have previously shown that the lipid-induced unfolded protein respons...
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| Udgivet i: | Biosci Rep |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Portland Press Ltd.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7189495/ https://ncbi.nlm.nih.gov/pubmed/32270855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20194118 |
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