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Unequivocal evidence for endogenous geranylgeranoic acid biosynthesized from mevalonate in mammalian cells
Geranylgeranoic acid (GGA) has been reported to induce autophagic cell death via upregulation of lipid-induced unfolded protein response in several human hepatoma-derived cell lines, and its 4,5-didehydro derivative has been developed as a preventive agent against second primary hepatoma in clinical...
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| Publicado no: | J Lipid Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6399490/ https://ncbi.nlm.nih.gov/pubmed/30622150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M090548 |
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