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Enhanced Glucose Requirement in Human Hepatoma-derived HuH-7 Cells by Forced Expression of the bcl-2 Gene

To explore the metabolic effects of Bcl-2 in tumor cells, a stable clone of HuH-7/bcl-2 and its control HuH-7/neo were established. Mitochondrial localization of ectopic Bcl-2 was demonstrated both by western blotting and immunofluorescence. HuH-7/bcl-2 cells consumed glucose at a higher rate, exhau...

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Autors principals: Okamoto, Kyoko, Muraguchi, Takashi, Shidoji, Yoshihiro
Format: Artigo
Idioma:Inglês
Publicat: the Society for Free Radical Research Japan 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533714/
https://ncbi.nlm.nih.gov/pubmed/18818743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.2008053
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