NRF3-POMP-20S Proteasome Assembly Axis Promotes Cancer Development via Ubiquitin-Independent Proteolysis of p53 and Retinoblastoma Protein

Proteasomes are essential protease complexes that maintain cellular homeostasis, and aberrant proteasomal activity supports cancer development. The regulatory mechanisms and biological function of the ubiquitin-26S proteasome have been studied extensively, while those of the ubiquitin-independent 20...

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Bibliografski detalji
Izdano u:Mol Cell Biol
Glavni autori: Waku, Tsuyoshi, Nakamura, Nanami, Koji, Misaki, Watanabe, Hidenori, Katoh, Hiroki, Tatsumi, Chika, Tamura, Natsuko, Hatanaka, Atsushi, Hirose, Shuuhei, Katayama, Hiroyuki, Tani, Misato, Kubo, Yuki, Hamazaki, Jun, Hamakubo, Takao, Watanabe, Akira, Murata, Shigeo, Kobayashi, Akira
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2020
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189095/
https://ncbi.nlm.nih.gov/pubmed/32123008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00597-19
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