Multiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferation

Accumulated evidence suggests a physiological relationship between the transcription factor NRF3 (NFE2L3) and cancers. Under physiological conditions, NRF3 is repressed by its endoplasmic reticulum (ER) sequestration. In response to unidentified signals, NRF3 enters the nucleus and modulates gene ex...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Chowdhury, A. M. Masudul Azad, Katoh, Hiroki, Hatanaka, Atsushi, Iwanari, Hiroko, Nakamura, Nanami, Hamakubo, Takao, Natsume, Tohru, Waku, Tsuyoshi, Kobayashi, Akira
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624902/
https://ncbi.nlm.nih.gov/pubmed/28970512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12675-y
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