Multiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferation

Accumulated evidence suggests a physiological relationship between the transcription factor NRF3 (NFE2L3) and cancers. Under physiological conditions, NRF3 is repressed by its endoplasmic reticulum (ER) sequestration. In response to unidentified signals, NRF3 enters the nucleus and modulates gene ex...

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Udgivet i:Sci Rep
Main Authors: Chowdhury, A. M. Masudul Azad, Katoh, Hiroki, Hatanaka, Atsushi, Iwanari, Hiroko, Nakamura, Nanami, Hamakubo, Takao, Natsume, Tohru, Waku, Tsuyoshi, Kobayashi, Akira
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624902/
https://ncbi.nlm.nih.gov/pubmed/28970512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12675-y
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