Multiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferation

Accumulated evidence suggests a physiological relationship between the transcription factor NRF3 (NFE2L3) and cancers. Under physiological conditions, NRF3 is repressed by its endoplasmic reticulum (ER) sequestration. In response to unidentified signals, NRF3 enters the nucleus and modulates gene ex...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chowdhury, A. M. Masudul Azad, Katoh, Hiroki, Hatanaka, Atsushi, Iwanari, Hiroko, Nakamura, Nanami, Hamakubo, Takao, Natsume, Tohru, Waku, Tsuyoshi, Kobayashi, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5624902/
https://ncbi.nlm.nih.gov/pubmed/28970512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12675-y
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