NRF3-POMP-20S Proteasome Assembly Axis Promotes Cancer Development via Ubiquitin-Independent Proteolysis of p53 and Retinoblastoma Protein

Proteasomes are essential protease complexes that maintain cellular homeostasis, and aberrant proteasomal activity supports cancer development. The regulatory mechanisms and biological function of the ubiquitin-26S proteasome have been studied extensively, while those of the ubiquitin-independent 20...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Waku, Tsuyoshi, Nakamura, Nanami, Koji, Misaki, Watanabe, Hidenori, Katoh, Hiroki, Tatsumi, Chika, Tamura, Natsuko, Hatanaka, Atsushi, Hirose, Shuuhei, Katayama, Hiroyuki, Tani, Misato, Kubo, Yuki, Hamazaki, Jun, Hamakubo, Takao, Watanabe, Akira, Murata, Shigeo, Kobayashi, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189095/
https://ncbi.nlm.nih.gov/pubmed/32123008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00597-19
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