NRF3-POMP-20S Proteasome Assembly Axis Promotes Cancer Development via Ubiquitin-Independent Proteolysis of p53 and Retinoblastoma Protein

Proteasomes are essential protease complexes that maintain cellular homeostasis, and aberrant proteasomal activity supports cancer development. The regulatory mechanisms and biological function of the ubiquitin-26S proteasome have been studied extensively, while those of the ubiquitin-independent 20...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Autores principales: Waku, Tsuyoshi, Nakamura, Nanami, Koji, Misaki, Watanabe, Hidenori, Katoh, Hiroki, Tatsumi, Chika, Tamura, Natsuko, Hatanaka, Atsushi, Hirose, Shuuhei, Katayama, Hiroyuki, Tani, Misato, Kubo, Yuki, Hamazaki, Jun, Hamakubo, Takao, Watanabe, Akira, Murata, Shigeo, Kobayashi, Akira
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7189095/
https://ncbi.nlm.nih.gov/pubmed/32123008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00597-19
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