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New addiction to the NRF2‐related factor NRF3 in cancer cells: Ubiquitin‐independent proteolysis through the 20S proteasome

Accumulating evidence has revealed that human cancers develop by sequentially mutating pivotal genes, including driver genes, and acquiring cancer hallmarks. For instance, cancer cells are addicted to the transcription factor NRF2 (NFE2L2), which is a driver gene that utilizes the cellular cytoprote...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kobayashi, Akira, Waku, Tsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942428/
https://ncbi.nlm.nih.gov/pubmed/31742837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14244
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