A carregar...

The deubiquitinating enzyme Usp14 allosterically inhibits multiple proteasomal activities and ubiquitin-independent proteolysis

The proteasome-associated deubiquitinating enzyme Usp14/Ubp6 inhibits protein degradation by catalyzing substrate deubiquitination and by poorly understood allosteric actions. However, upon binding a ubiquitin chain, Usp14 enhances proteasomal degradation by stimulating ATP and peptide degradation....

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kim, Hyoung Tae, Goldberg, Alfred L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465503/
https://ncbi.nlm.nih.gov/pubmed/28416611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.763128
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!