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Ubiquitinated Proteins Activate the Proteasomal ATPases by Binding to Usp14 or Uch37 Homologs

Degradation of ubiquitinated proteins by 26 S proteasomes requires ATP hydrolysis, but it is unclear how the proteasomal ATPases are regulated and how proteolysis, substrate deubiquitination, degradation, and ATP hydrolysis are coordinated. Polyubiquitinated proteins were shown to stimulate ATP hydr...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Peth, Andreas, Kukushkin, Nikolay, Bossé, Marc, Goldberg, Alfred L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3597817/
https://ncbi.nlm.nih.gov/pubmed/23341450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.441907
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