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Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c

In mammalian cells, the 26S proteasomes vary in composition. In addition to the standard 28 subunits in the 20S core particle and 19 subunits in each 19S regulatory particle, a small fraction (about 10–20% in our preparations) also contains the deubiquitinating enzyme Usp14/Ubp6, which regulates pro...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Main Authors: Kuo, Chueh-Ling, Goldberg, Alfred Lewis
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5410784/
https://ncbi.nlm.nih.gov/pubmed/28396413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701734114
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