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The Proteasome-Associated Deubiquitinating Enzyme Usp14 Is Essential for the Maintenance of Synaptic Ubiquitin Levels and the Development of Neuromuscular Junctions

Dysfunction of the ubiquitin proteasome system (UPS) has been implicated in the pathogenesis of many neurological diseases, including Alzheimer's, spinocerebellar ataxia, and several motor neuron diseases. Recent research indicates that changes in synaptic transmission may play a critical role...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chen, Ping-Chung, Qin, Lu-Ning, Li, Xiao-Ming, Walters, Brandon J., Wilson, Julie A., Mei, Lin, Wilson, Scott M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766780/
https://ncbi.nlm.nih.gov/pubmed/19726649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2635-09.2009
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