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UBL domain of Usp14 and other proteins stimulates proteasome activities and protein degradation in cells
The best-known function of ubiquitin-like (UBL) domains in proteins is to enable their binding to 26S proteasomes. The proteasome-associated deubiquitinating enzyme Usp14/UBP6 contains an N-terminal UBL domain and is an important regulator of proteasomal activity. Usp14 by itself represses multiple...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6294929/ https://ncbi.nlm.nih.gov/pubmed/30487212 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1808731115 |
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