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Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation

Although ubiquitination is widely assumed to be the only regulated step in the ubiquitin–proteasome pathway, recent studies have demonstrated several important mechanisms that regulate the activities of the 26S proteasome. Most proteasomes in cells are inactive but, upon binding a ubiquitinated subs...

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Bibliografische gegevens
Gepubliceerd in:Biomolecules
Hoofdauteurs: Goldberg, Alfred L., Kim, Hyoung Tae, Lee, Donghoon, Collins, Galen Andrew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224753/
https://ncbi.nlm.nih.gov/pubmed/34067263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060779
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