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Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation

Although ubiquitination is widely assumed to be the only regulated step in the ubiquitin–proteasome pathway, recent studies have demonstrated several important mechanisms that regulate the activities of the 26S proteasome. Most proteasomes in cells are inactive but, upon binding a ubiquitinated subs...

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Bibliografiske detaljer
Udgivet i:Biomolecules
Main Authors: Goldberg, Alfred L., Kim, Hyoung Tae, Lee, Donghoon, Collins, Galen Andrew
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224753/
https://ncbi.nlm.nih.gov/pubmed/34067263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060779
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