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Mechanisms That Activate 26S Proteasomes and Enhance Protein Degradation

Although ubiquitination is widely assumed to be the only regulated step in the ubiquitin–proteasome pathway, recent studies have demonstrated several important mechanisms that regulate the activities of the 26S proteasome. Most proteasomes in cells are inactive but, upon binding a ubiquitinated subs...

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Bibliografski detalji
Izdano u:Biomolecules
Glavni autori: Goldberg, Alfred L., Kim, Hyoung Tae, Lee, Donghoon, Collins, Galen Andrew
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224753/
https://ncbi.nlm.nih.gov/pubmed/34067263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11060779
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