NFE2L1 and NFE2L3 Complementarily Maintain Basal Proteasome Activity in Cancer Cells through CPEB3-Mediated Translational Repression

Proteasomes are protease complexes essential for cellular homeostasis, and their activity is crucial for cancer cell growth. However, the mechanism of how proteasome activity is maintained in cancer cells has remained unclear. The CNC family transcription factor NFE2L1 induces the expression of almo...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Waku, Tsuyoshi, Katayama, Hiroyuki, Hiraoka, Miyako, Hatanaka, Atsushi, Nakamura, Nanami, Tanaka, Yuya, Tamura, Natsuko, Watanabe, Akira, Kobayashi, Akira
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324849/
https://ncbi.nlm.nih.gov/pubmed/32366381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00010-20
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