Glucagon-Receptor Signaling Reverses Hepatic Steatosis Independent of Leptin Receptor Expression

Glucagon (GCG) is an essential regulator of glucose and lipid metabolism that also promotes weight loss. We have shown that glucagon-receptor (GCGR) signaling increases fatty acid oxidation (FAOx) in primary hepatocytes and reduces liver triglycerides in diet-induced obese (DIO) mice; however, the m...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Nason, Shelly R, Kim, Teayoun, Antipenko, Jessica P, Finan, Brian, DiMarchi, Richard, Hunter, Chad S, Habegger, Kirk M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188084/
https://ncbi.nlm.nih.gov/pubmed/31673703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqz013
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