Glucagon-Receptor Signaling Reverses Hepatic Steatosis Independent of Leptin Receptor Expression

Glucagon (GCG) is an essential regulator of glucose and lipid metabolism that also promotes weight loss. We have shown that glucagon-receptor (GCGR) signaling increases fatty acid oxidation (FAOx) in primary hepatocytes and reduces liver triglycerides in diet-induced obese (DIO) mice; however, the m...

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Vydáno v:Endocrinology
Hlavní autoři: Nason, Shelly R, Kim, Teayoun, Antipenko, Jessica P, Finan, Brian, DiMarchi, Richard, Hunter, Chad S, Habegger, Kirk M
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7188084/
https://ncbi.nlm.nih.gov/pubmed/31673703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqz013
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