Glucagon receptor signaling regulates weight loss via central KLB receptor complexes

Glucagon regulates glucose and lipid metabolism and promotes weight loss. Thus, therapeutics stimulating glucagon receptor (GCGR) signaling are promising for obesity treatment; however, the underlying mechanism(s) have yet to be fully elucidated. We previously identified that hepatic GCGR signaling...

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Dades bibliogràfiques
Publicat a:JCI Insight
Autors principals: Nason, Shelly R., Antipenko, Jessica, Presedo, Natalie, Cunningham, Stephen E., Pierre, Tanya H., Kim, Teayoun, Paul, Jodi R., Holleman, Cassie, Young, Martin E., Gamble, Karen L., Finan, Brian, DiMarchi, Richard, Hunter, Chad S., Kharitonenkov, Alexei, Habegger, Kirk M.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7934938/
https://ncbi.nlm.nih.gov/pubmed/33411693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.141323
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