OR28-5 Bile Acid Sequestration Accelerates Glucagon Receptor-Mediated Body Weight Loss in Obese Mice

Glucagon, an essential regulator of glucose and lipid metabolism, also promotes weight loss. Previously, we reported that chronic glucagon receptor (GCGR) activation increased energy expenditure and plasma bile acid (BA) levels. Hepatic Farnesoid X Receptor (FXR) has been associated with this GCGR-B...

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Опубликовано в: :J Endocr Soc
Главные авторы: Kim, Teayoun, Nason, Shelly, Antipenko, Jessica, Presedo, Natalie, Finan, Brian, DiMarchi, Richard, Habegger, Kirk
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2019
Предметы:
Diabetes Mellitus and Glucose Metabolism
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554830/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR28-5
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