OR28-5 Bile Acid Sequestration Accelerates Glucagon Receptor-Mediated Body Weight Loss in Obese Mice

Glucagon, an essential regulator of glucose and lipid metabolism, also promotes weight loss. Previously, we reported that chronic glucagon receptor (GCGR) activation increased energy expenditure and plasma bile acid (BA) levels. Hepatic Farnesoid X Receptor (FXR) has been associated with this GCGR-B...

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Vydáno v:J Endocr Soc
Hlavní autoři: Kim, Teayoun, Nason, Shelly, Antipenko, Jessica, Presedo, Natalie, Finan, Brian, DiMarchi, Richard, Habegger, Kirk
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2019
Témata:
Diabetes Mellitus and Glucose Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554830/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR28-5
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