OR28-5 Bile Acid Sequestration Accelerates Glucagon Receptor-Mediated Body Weight Loss in Obese Mice

Glucagon, an essential regulator of glucose and lipid metabolism, also promotes weight loss. Previously, we reported that chronic glucagon receptor (GCGR) activation increased energy expenditure and plasma bile acid (BA) levels. Hepatic Farnesoid X Receptor (FXR) has been associated with this GCGR-B...

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Dettagli Bibliografici
Pubblicato in:J Endocr Soc
Autori principali: Kim, Teayoun, Nason, Shelly, Antipenko, Jessica, Presedo, Natalie, Finan, Brian, DiMarchi, Richard, Habegger, Kirk
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2019
Soggetti:
Diabetes Mellitus and Glucose Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554830/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR28-5
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