OR28-5 Bile Acid Sequestration Accelerates Glucagon Receptor-Mediated Body Weight Loss in Obese Mice

Glucagon, an essential regulator of glucose and lipid metabolism, also promotes weight loss. Previously, we reported that chronic glucagon receptor (GCGR) activation increased energy expenditure and plasma bile acid (BA) levels. Hepatic Farnesoid X Receptor (FXR) has been associated with this GCGR-B...

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Dades bibliogràfiques
Publicat a:J Endocr Soc
Autors principals: Kim, Teayoun, Nason, Shelly, Antipenko, Jessica, Presedo, Natalie, Finan, Brian, DiMarchi, Richard, Habegger, Kirk
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2019
Matèries:
Diabetes Mellitus and Glucose Metabolism
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554830/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR28-5
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