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OR28-5 Bile Acid Sequestration Accelerates Glucagon Receptor-Mediated Body Weight Loss in Obese Mice

Glucagon, an essential regulator of glucose and lipid metabolism, also promotes weight loss. Previously, we reported that chronic glucagon receptor (GCGR) activation increased energy expenditure and plasma bile acid (BA) levels. Hepatic Farnesoid X Receptor (FXR) has been associated with this GCGR-B...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Kim, Teayoun, Nason, Shelly, Antipenko, Jessica, Presedo, Natalie, Finan, Brian, DiMarchi, Richard, Habegger, Kirk
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6554830/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-OR28-5
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